Acoziborole resistance associated mutations in Trypanosoma brucei CPSF3

Acoziborole resistance associated mutations in Trypanosoma brucei CPSF3

Author summary Diagnosis and treatment options, previously limited for sleeping sickness, have been transformed in recent years. Acoziborole, for example, is a new, safe, single dose, oral therapy for the treatment of this deadly disease. This drug can also b…

Abstract Acoziborole is a safe, single dose, oral therapy, for treatment of both early and late-stage sleeping sickness, a deadly disease caused by African trypanosomes. Other benzoxaboroles show ef… [+40285 chars]