Host kinase regulation of Plasmodium vivax dormant and replicating liver stages

Host kinase regulation of Plasmodium vivax dormant and replicating liver stages

Author summary One of the major hurdles to malaria eradication is the ability of Plasmodium vivax to form dormant liver-stages called hypnozoites, which reside within the liver for weeks to months before being reactivated and causing a new round of blood stag…

Abstract Upon transmission to the liver, Plasmodium vivax parasites form replicating schizonts, which progress to initiate blood-stage infection, or dormant hypnozoites that reactivate weeks to mont… [+76329 chars]