Author summary We have used cryo-electron microscopy and solution biophysical techniques to understand the structure of the Rep protein from a Redondovirus, a CRESS DNA virus originally found in human respiratory samples. The small circular Rep-encoding singl…
Abstract
Circular Rep-encoding single-stranded DNA (CRESS-DNA) virus Rep proteins are multidomain enzymes that mediate viral DNA rolling-circle replication. Reps nick viral DNA to expose a 3 end for… [+103420 chars]









