Topological metrics as evolutionary and dynamical descriptors of conformational landscapes within protein families

Topological metrics as evolutionary and dynamical descriptors of conformational landscapes within protein families

Author summary Advances in protein science and artificial intelligence have resulted in a wealth of protein structures, yet a fundamental challenge remains: how does a protein‘s native structure encode its dynamical behavior? Addressing this question is cruci…

Citation: Ramesh N, Ozkan SB, Panagiotou E (2026) Topological metrics as evolutionary and dynamical descriptors of conformational landscapes within protein families. PLoS Comput Biol 22(3): e101398… [+41392 chars]