The molecular basis of force selectivity by PIEZO2

The molecular basis of force selectivity by PIEZO2

PIEZO2 is intrinsically more rigid than PIEZO1, and disparate mechanical stimuli paradoxically evoke opposite conformational and gating responses in each channel.

Study design No statistical methods were used to predetermine sample size and the sample size was based on a previous study16. All attempts at replication were successful, and all experiments were r… [+39905 chars]